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Preheat oven to 375.
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Lightly grease a 9 x 13 pan.
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Pour half of the spaghetti sauce in the bottom of a 9 x 13 pan.
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Combine 1 1/2 cups mozzarella cheese, cottage cheese, cream cheese, spinach, oregano, salt and pepper.
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Spoon mixture into each manicotti.
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Arrange the manicotti in a single layer over the sauce.
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Dilute the remaining sauce with 1 cup of water and pour over the manicotti.
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Sprinkle with the remaining 1/2 cup of mozzarella cheese.
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Cover tightly with foil and bake at 375 for 1 hour.
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Let stand 10 minutes before serving.